闫强

    10A0A

     

    闫强 实验师

    E-mail:safer123@yeah.net yanqiang@henu.edu.cn

    学科:动物基因组编辑技术;昆虫生理生化;细胞生物学


    教育及工作经历:

    2020-至今:河南大学,实验师,研究方向:昆虫基因编辑技术;昆虫生殖发育的调控机制;昆虫-微生物互作机制。

    2018-2020:河南大学,师资博士后,研究方向:昆虫基因组编辑技术与细胞生物学。

    2012-2018:西北农林科技大学动物科技学院,动物遗传育种与繁殖专业,生物技术与动物育种方向,博士

    2008-2012:西北农林科技大学动物科技学院,动物科学专业,学士


    研究领域:

    1. 基于CRISPR/Cas9系统的昆虫基因组编辑技术开发及应用;

    2. 昆虫-微生物互作的影响及其作用机制。。


    科研项目:

    1. 中国博士后科学基金会, 中国博士后基金面上资助, 2020M672205, 神经肽Crz 调控飞蝗警戒信号的作用通路研究, 2020-06 至 2022-03, 8万元, 结题, 主持。


    代表性论文(*通讯作者)

    1. Yan Qiang#; He Yingying#; Yue Yang; Jie Luyao; Wen Tingmei; Zhao Yumiao; Zhang Min; Zhang Tingting*; Construction of Homozygous Mutants of Migratory Locust using CRISPR/Cas9 Technology, Journal of Visualized Experiments, 181: e63629-e63629, DOI:10.3791/63629(2022)

    2. Qiang Yan#, Kun Xu#, Jiani Xing, Tingting Zhang, Xin Wang, Zehui Wei, Chonghua Ren, Zhongtian Liu, Simin Shao, Zhiying Zhang*. Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure. Scientific Reports, 6:38970, doi: 10.1038/srep38970 (2016).

    3. Chonghua Ren, Qiang Yan, Zhiying Zhang*. Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast. Molecular Biology Reports. 41(10):6939-48. doi: 10.1007/s11033-014-3579-6 (2014).

    4. Zhongtian Liu, Gang Zhou, Chonghua Ren, Kun Xu, Qiang Yan, Xinyi Li, Tingting Zhang, Zhiying Zhang*. Oral administration of myostatin-specific recombinant Saccharomyces cerevisiae vaccine in rabbit. Vaccine. doi: 10.1016/j.vaccine.2016.03.036 (2016).

    5. Kun Xu, Chonghua Ren, Zhongtian Liu, Tao Zhang, Tingting Zhang, Duo Li, Ling Wang, Qiang Yan, Lijun Guo, Juncen Shen, Zhiying Zhang*. Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. Cellular and Molecular Life Sciences. 72 (2) : 383–399 http://dx.doi.org/10.1007/s00018-014-1679-z (2014). (JCR: Q1, 2014年被评为Global Medical Discovery 'Key scientific article')

    6. Kun Xu, Tingting Zhang, Ling Wang, Cunfang Zhang, Long Zhang, Lixia Ma, Ying Xin, Chonghua Ren, Zhiqiang Zhang, Qiang Yan, Martineau D and Zhiying Zhang*. Walleye dermal sarcoma virus: expression of a full-length clone or the rv-cyclin (orf a) gene is cytopathic to the host and human tumor cells. Molecular Biology Reports.; 40(2):1451-61(2013).

    7.雒志新,闫强,代冬梅,张智英,王昕*. 靶向敲除猪ApoE基因的CRISPR/Cas9系统构建及基因组检测. 家畜生态学报. (2018).